Pharmaceutical Grade White Crystal Powder Calcium Hydrogen Phosphate

Calcium hydrogen phosphate, also known as dibasic calcium phosphate, is a white, tasteless, and odorless powder that is insoluble in water. Its chemical formula is CaHPO4, and its molecular formula is CaHPO4. It is commonly used in the pharmaceutical industry for its various applications and beneficial properties.

In the pharmaceutical industry, calcium hydrogen phosphate serves multiple purposes due to its properties and characteristics. It is widely utilized as a pharmaceutical excipient, a source of calcium, and a component in the formulation of solid dosage forms such as tablets and capsules.

One of the primary applications of calcium hydrogen phosphate in the pharmaceutical industry is as a direct compression filler and binder in the production of tablets. As an excipient, it provides the necessary bulk and binding properties to help form tablets from active pharmaceutical ingredients. Its compressibility and flowability make it an ideal choice for direct compression, a common method for manufacturing tablets without the need for wet granulation.

Furthermore, calcium hydrogen phosphate is used as a source of calcium in pharmaceutical formulations. Calcium is an essential mineral that plays a vital role in various physiological functions, including bone health, muscle function, and nerve transmission. By incorporating calcium hydrogen phosphate into pharmaceutical products, manufacturers can ensure the delivery of bioavailable calcium, which is important for bone strength and overall health.

In addition to its role as a tablet filler, binder, and source of calcium, calcium hydrogen phosphate is also utilized as a disintegrant in solid dosage forms. Disintegrants are added to tablets and capsules to promote their breakup or disintegration in the gastrointestinal tract, thereby facilitating the release and absorption of the active pharmaceutical ingredients. Calcium hydrogen phosphate’s ability to aid in the disintegration of tablets contributes to the bioavailability and efficacy of the medications.

Moreover, calcium hydrogen phosphate is recognized for its role as a buffering agent in pharmaceutical formulations. Buffering agents help maintain the pH of medications, particularly in oral dosage forms, to ensure stability and compatibility with the physiological environment of the gastrointestinal tract. By incorporating calcium hydrogen phosphate as a buffering agent, pharmaceutical manufacturers can optimize the pH of their formulations, which is crucial for the stability and effectiveness of the medications.

It is important to note that the use of calcium hydrogen phosphate in pharmaceutical applications is subject to regulatory guidelines and quality standards to ensure its safety, efficacy, and appropriate dosage. Manufacturers must adhere to established protocols for the inclusion of calcium hydrogen phosphate in pharmaceutical products, including proper labeling, dosage recommendations, and potential interactions with other medications.

In conclusion, calcium hydrogen phosphate is a versatile and valuable ingredient in the pharmaceutical industry, offering essential functionality as a tablet filler, binder, source of calcium, disintegrant, and buffering agent. Its diverse applications make it a fundamental component in the formulation of solid dosage forms, supporting the development of high-quality pharmaceutical products aimed at improving patient health and well-being. When used responsibly and in accordance with regulatory standards, calcium hydrogen phosphate contributes to the creation of effective and reliable medications that benefit individuals worldwide.